Once the promethazine is fully metabolized after a large dose, a greater number of metabolites are formed.
Information about Promethazine.
Promethazine hydrochloride occurs as a white to faint yellowpractically odorlesscrystalline powder which slowly oxidizes and turns blue on prolonged exposure to airIt is soluble in water and freely soluble in alcohol.
It is not known whether promethazine HClpromethazine hydrochlorideis excreted in human milkBecause many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from promethazine hydrochloride tabletsa decision should be made whether to discontinue nursing or to discontinue the drugtaking into account the importance of the drug to the mother.
Hyperexcitability and abnormal movements have been reported in patients following a single administration of promethazine HClpromethazine hydrochlorideConsideration should be given to the discontinuation of promethazine HClpromethazine hydrochlorideand to the use of other drugs if these reactions occurRespiratory depressionnightmaresdeliriumand agitated behavior have also been reported in some of these patients.
SECONDARY TO PROMETHAZINE HYDROCHLORIDE TABLETS ADMINISTRATION MAY BE CONFUSED WITH THE CNS SIGNS OF UNDIAGNOSED PRIMARY DISEASEe.gENCEPHALOPATHY OR REYE’S SYNDROMETHE USE OF PROMETHAZINE HCLpromethazine hydrochlorideTABLETS SHOULD BE AVOIDED IN PEDIATRIC PATIENTS WHOSE SIGNS AND SYMPTOMS MAY SUGGEST REYE’S SYNDROME OR OTHER HEPATIC DISEASES.
This medication may be prescribed for other usesask your doctor or pharmacist for more information.
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