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In fiverandomizeddouble-blindplacebo-controlledparallel group migraine prophylaxis clinical trialsmost adverse reactions occurred more frequently during the titration period than during the maintenance periodAmong adverse reactions with onset during titrationapproximately half persisted into the maintenance period.
Tirednessdrowsinessdizzinessloss of coordinationtingling of the hands/feetloss of appetitebad taste in your mouthdiarrheaand weight loss may occurMental problems such as confusionslowed thinkingtrouble concentrating or paying attentionnervousnessmemory problemsor speech/language problems may also occurIf any of these effects persist or worsentell your doctor or pharmacist promptly.
Some people have thoughts about suicide while taking seizure medicineStay alert to changes in your mood or symptomsReport any new or worsening symptoms to your doctor.
Topamax can decrease sweating and may cause life-threatening dehydrationespecially in childrenAvoid becoming overheated or dehydratedTell your doctor if you have decreased sweatinghigh feverand hot dry skin.
Dosage is based on your medical condition and response to treatmentFor childrenthe dosage is also based on weightYour doctor will gradually increase your dose to reduce your risk of side effectsFor some conditionsyou may start treatment with topiramate once daily at bedtime and slowly increase your dose to twice a dayIt may take several weeks or months to reach the best dose for you and to get the full benefit from this medication.
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