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Antineoplastic agents exert their benefits by killing rapidly growing cancer cellsUse of medications that stimulate cell growth is usually not recommended in patients who have been exposed to cytotoxic chemotherapy within 24 hoursSpecificallythe manufacturer of pegfilgrastimNeulastarecommends that pegfilgrastim shouldnot be administered to patients who have been treated with cytotoxic chemotherapy within the prior 14 daysAlsochemotherapy should not be administered within 24 hours of pegfilgrastim.
Hydroxyurea belongs to a class of drugs called antimetabolitesA class of drugs is a group of medications that work in a similar wayThese drugs are often used to treat similar conditions.
There are no data that support specific guidance for dosage adjustment in patients with hepatic impairmentClose monitoring of hematologic parameters is advised in these patients.
Bone marrow suppressiondrop in white blood cellred blood cell and platelet countsanorexianauseavomitingdiarrheaconstipationsores in the mouthskin rashswelling in the handsfeetlegs and facechanges in skin pigmentationhair losspainful urinationdrowsinessheadachedizzinessdisorientationhallucinationsseizuresliver problemsshortness of breathmetabolic disturbancesand kidney problems.
Store this medication at room temperature in the original containerIf a caregiver prepares your dose for youthey should wear gloves or pour the pills directly from their container into the capa small cupor directly into your handThey should avoid touching the pillsThey should always wash their hands before and after giving you the medicationPregnant or nursing women should not prepare the dose for youAsk your oncology team where to return any unused medication for disposalDo not flush down the toilet or throw in the trash.
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