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The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotoninExamples include street drugs such as MDMAecstasyStJohn’s wortdextromethorphancertain antidepressantsincluding SSRIs such as fluoxetine/paroxetineSNRIs such as duloxetine/venlafaxineTCAs such as amitriptyline/doxepincertain narcoticmedicationssuch as meperidinemethadonepentazocinepropoxyphenetramadoltapentadolamong othersThe risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.
Store the Emsam skin patches at room temperature away from heat and moistureKeep each patch in the foil pouch until you are ready to apply one.
It is very important that you follow special dietary restrictions in order to limit the amount of tyramine in your diet if you are using the higher strength patches9 or 12 milligramsAvoid drinking large amounts of beverages containing caffeinecoffeeteacolasor eating large amounts of chocolateCaffeine can increase the side effects of this medicationFoods and beverages high in tyramine should be avoided while you are using this medication and for at least 2 weeks after you stop using this medication.
EMSAM is the first and only once-daily skin patch approved to treat major depressive disorderMDD
EMSAM is contraindicated in patients less than 12 years of age because of an increased risk of hypertensive crisis.
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