Topamax has an established safety and efficacy profile and is a generally well-tolerated antiseizure medicine, proven to be effective in controlling a broad range of seizures in adults and children age 2 or older.
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Table 5Adverse Reactions in the High Dose Group As Compared to the Low Dose Groupin Monotherapy Epilepsy Trials in Adult and Pediatric Patients.
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Avoid becoming overheated or dehydrated in hot weatherTopiramate can decrease sweating and increase body temperatureleading to life-threatening dehydrationespecially in children
Fatigue/sleepiness Nausea Weight loss Nervousness Upper respiratory tract infection Burning or prickling in the handsarmslegs and feetparesthesiaDizziness Psychomotor slowing Fever Loss of appetite Taste change Anorexia Diarrhea Speech disorders/related speech problems Abdominal pain NumbnesshypoesthesiaAbnormal vision Difficulty with memory.
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