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Rarelyproton pump inhibitorssuch as pantoprazolehave caused vitamin B-12 deficiencyThe risk is increased if they are taken every day for a long time3 years or longerTell your doctor right away if you develop symptoms of vitamin B-12 deficiencysuch as unusual weaknesssore tongueor numbness/tingling of the hands/feet
Hematologicleukopeniareported in ex-US clinical trials onlythrombocytopenia.
Hepatobiliary Disordershepatocellular damage leading to jaundice and hepatic failure.
More frequent side effects includediarrhea and nauseaSee below for a comprehensive list of adverse effects.
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