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Some people would say that these side effects only happen to a small percentage of people taking clindamycin.

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Clindamycin has been shown to be active against most of the isolates of the following microorganismsboth in vitro and in clinical infectionsas described in the INDICATIONS AND USAGE section.

EndocarditisRecent AHA guidelines recommend only for invasive procedures in high-risk patients.

Many antibioticsincluding clindamycinmay cause overgrowth of dangerous bacteria in the large intestineThis may cause mild diarrhea or may cause a life-threatening condition called colitisinflammation of the large intestineClindamycin is more likely to cause this type of infection than many other antibioticsso it should only be used to treat serious infections that cannot be treated by other antibioticsTell your doctor if you have or have ever had colitis or other conditions that affect your stomach or intestines.

Clindamycin is also indicated in the treatment of serious infections due to susceptible strains of streptococcipneumococciand staphylococciIts use should be reserved for penicillin-allergic patients or other patients for whominthe judgment of the physiciana penicillin is inappropriateBecause of the risk of colitisas described in the BOXED WARNINGbefore selecting clindamycinthe physician should consider the nature of the infection and the suitability of less toxic alternativese.gerythromycin

Immune SystemDrug reaction with eosinophilia and systemic symptomsDRESScases have been reported.

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