Hytrin is used for treating high blood pressure and treating signs and symptoms of benign prostatic hyperplasia bph .
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The single daily dosage may be increased by approximately doubling the dosage at weekly intervals to achieve the desired blood pressure response.
Orally administered Hytrin is also indicated in adults as a therapy for the symptomatic treatment of urinary obstruction caused by benign prostatic hyperplasiaBPHTerazosin is a selective post synaptic alpha-1-adrenoceptor blockerAntagonism of alpha-1-receptors on prostatic and urethral smooth muscle has been shown to improve urinary tract flow and relieve the urinary obstruction caused by BPH.
Cardiovascular support is of first importanceRestoration of blood pressure and normalisation of heart rate may be accomplished by keeping the patient in a supine positionIf this measure is inadequateshock should first be treated with volume expanders and if necessaryvasopressors could then be usedRenal function should be monitored and general supportive measures applied as requiredDialysis may not be of benefit since laboratory data indicate that terazosin is highly protein bound.
Metabolic side effects have included decreases in serum triglycerides and VLDL cholesteroland increases in HDL cholesterolTerazosinthe active ingredient contained in Hytrinmay counterbalance deleterious effects on the lipid profile associated with thiazide diureticsmaking it a reasonable drug to use in combination with these agentsRef]
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