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Inhibition of the anticoagulant effect of warfarinwhen administered with azathioprinehas been reported.

Chromosomal abnormalities have been demonstrated in both male and female patients treated with ImuranIt is difficult to assess the role of Imuran in the development of these abnormalities.

Benefit versus risk must be weighed carefully before use of IMURAN in patients of reproductive potentialThere are no adequate and well-controlled studies in pregnant womenIf this drug is used during pregnancy or if the patient becomes pregnant while taking this drugthe patient should be apprised of the potential hazard to the fetusWomen of childbearing age should be advised to avoid becoming pregnant.

WARNING/CAUTIONEven though it may be raresome people may have very bad and sometimes deadly side effects when taking a drugTell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

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