The dosage and administration recommendations outlined above regarding the use of clozaril in patients with treatment-resistant schizophrenia should also be followed when treating patients with schizophrenia or schizoaffective disorder at risk for recurrent suicidal behavior.
Information about Clozaril.
If you are using the liquid form of this medicationread the Patient Information Leaflet if available from your pharmacist before you start taking clozapine and each time you get a refillIf you have any questionsask your doctor or pharmacist.
Patients with a history of epilepsy should be closely observed during Clozaril therapy since dose-related convulsions have been reportedIn such casesthe dose should be reducedsee section 4.2andif necessaryan anti-convulsant treatment should be initiated.
There have been post marketing reports of myocardial infarction including fatal casesCausality assessment was difficult in the majority of these cases because of serious pre-existing cardiac disease and plausible alternative causes.
Alcohol should not be used concomitantly with Clozaril due to possible potentiation of sedation.
Clozapine can pass into breast milk and may harm a nursing babyYou should not breast-feed while you are taking Clozaril.
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