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Information about Nexium.
Esomeprazole may cause new or worsening symptoms of lupusTell your doctor if you have joint pain and a skin rash on your cheeks or arms that worsens in sunlight.
Literature suggests that concomitant use of PPIs with methotrexateprimarily at high dosesee methotrexate prescribinginformationmay elevate and prolong serum levels of methotrexate and/or its metabolitepossibly leading to methotrexate toxicitiesIn high-dose methotrexate administration a temporary withdrawal of the PPI may be considered in some patientssee DRUG INTERACTIONS
Symptom relief does not rule out the presence of other serious conditionsRead More.
Acute interstitial nephritis has been observed in patients taking PPIs including NEXIUMAcute interstitial nephritis may occur at any point during PPI therapy and is generally attributed to an idiopathic hypersensitivity reactionDiscontinue NEXIUM if acute interstitial nephritis developssee CONTRAINDICATIONS
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