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The physician should advise the patient to report any medical history of heart diseasehigh blood pressureor kidney or liver disease and to report current use of any medicines to determine if these medicines might interact adversely with fludrocortisone acetatesee Drug Interactions
Adequate studies have not been performed in animals to determine whether fludrocortisone acetate has carcinogenic or mutagenic activity or whether it affects fertility in males or females.
Corticosteroids may mask some signs of infectionand new infections may appear during their useThere may be decreased resistance and inability to localize infection when corticosteroids are usedIf an infection occurs during fludrocortisone acetate therapyit should be promptly controlled by suitable antimicrobial therapy.
Pregnancy and breastfeeding If you are pregnant or breastfeedingthink you may be pregnant or are planning to have a babyask your doctor or pharmacist for advice before taking this medicine.
Corticosteroids may affect the nitrobluetetrazolium test for bacterial infection and produce false-negative results.
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